Home
About Us Privacy Policy Conduct Speak Sponsor Attend Sign up / Login
+44 (0)20 7827 6000 events@saemediagroup.com
cart Basket Total: £0.00
Reducing attrition in drug discovery through the use of human translational cellular models
8 February 2022

If you have registered for this conference, please click this link to login and join. Your login details should have been sent to you by portal@smi-online.co.uk

Reducing attrition in drug discovery through the use of human translational cellular models

SAE Media Group’s 5th Annual Conference
3D Cell Culture
February 09-10, 2022 | Virtual Conference
-------------------------------------------------------------------------
3D Cell Culture has gained increasing momentum in the pharmaceutical industry over recent years, with the global 3D Cell Culture market predicted to reach a value of $3.2 Billion by 2027, researchers globally are realising the growing potential of in vitro applications for drug discovery, predictivity and validation, safety and toxicity. 3D Cell Culture technology promises to offer increased translatability in models and reduce the costly rates of drug attrition in the discovery process -- heralding the next major advance in the discovery of pharmaceuticals.

A 3D cell culture is an artificially created environment in which biological cells are permitted to grow or interact with their surroundings in all three dimensions. Unlike 2D environments (e.g., a Petri dish), a 3D cell culture allows cells in vitro to grow in all directions, similar to how they would in vivo. The crux of 3D cell culture is mimicry – how to best replicate the living environment under experimental conditions, to have the best predictive capabilities when testing drugs.
These spatial and physical aspects in 3D cultures affect the signal transduction from the outside to the inside of cells, and ultimately influence gene expression and cellular behaviour – these are especially important factors to consider when testing a new drug.
 

FEATURED SPEAKERS

Wendy Rowan

Wendy Rowan

Scientific Director, Novel Human Genetics, GSK
view all speakers

Wendy Rowan

Scientific Director, Novel Human Genetics, GSK
Wendy Rowan

I started my career at Guy’s Hospital Medical School, before transitioning to industry. I have worked for GSK and its legacy companies for over thirty years. Immunology has been a common theme throughout my career, working on aspects of both innate and adaptive immunity in respiratory and autoimmune diseases. In April 2019, I joined the Novel Human Genetics Research Unit with a focus on using genetics to guide target selection for drug discovery. With the aim of reducing attrition in drug discovery, I have a long standing interest in developing and accessing better human translational models for target validation, lead discovery and candidate selection, including safety assessment and PK/PD profiling.

Workshop agenda

clock

8:30

Registration & Coffee

clock

9:00

Opening remarks and introductions

Wendy Rowan
View Bio

Wendy Rowan, Scientific Director, Novel Human Genetics, GSK

clock

9:10

The challenge in drug discovery to reduce clinical attrition

Wendy Rowan
View Bio

Wendy Rowan, Scientific Director, Novel Human Genetics, GSK

  •  Assessing novel techniques in quantitative systems pharmacology to improve translatability
  • Enabling the better prediction of drug efficacy, toxicity, and DMPK
  • Applying 3D cell techniques to minimise costly late-stage clinical trial failures
    • clock

    9:50

    The new generation of human translational models for use in drug discovery

    Wendy Rowan
    View Bio

    Wendy Rowan, Scientific Director, Novel Human Genetics, GSK

  • Assessing the limited physiological relevance of 2D cultures
  • Mimicking the natural microenvironments and architectures of functioning tissues
  • Outlining the advantages in 3D culturing for the detection of drug-induced toxicity
     
    • clock

    10:30

    Morning Coffee

    clock

    11:00

    The application and challenges in application of human translational models for drug discovery

    Wendy Rowan
    View Bio

    Wendy Rowan, Scientific Director, Novel Human Genetics, GSK

  • Why the Pharmaceutical Industry has stalled on the uptake of modern translational models
  • Identifying the hurdles facing 3D Cell technologies: Overcoming scalability and reproducibility challenges
     
    • clock

    11:40

    Looking to the future

    Wendy Rowan
    View Bio

    Wendy Rowan, Scientific Director, Novel Human Genetics, GSK

  • Evaluating the increased opportunities available through the production of higher-quality preclinical physiological data
    • clock

    12:30

    Closing remarks

    Wendy Rowan
    View Bio

    Wendy Rowan, Scientific Director, Novel Human Genetics, GSK


    Wendy Rowan
    Wendy Rowan
    Scientific Director, Novel Human Genetics
    GSK

    VENUE

    Online Virtual Event

    Online Virtual Event , Online Virtual Event , United Kingdom

    A number of our clients have been approached by third party organisations offering to book hotel rooms. We would advise that you do not book through them as they are not representing the SMi Group. SMi Group books all hotel rooms directly. If you are approached by a third party organisation then please contact us before making any bookings. If you have already booked a hotel room using a third party organisation, we would highly recommend contacting the hotel you were booked into to ensure a booking has been made for you. We would also advise you to please check the terms and conditions of the booking carefully.
    HOTEL BOOKING FORM

    Online Virtual Event

    Online Virtual Event
    United Kingdom

    Online Virtual Event

    HOTEL BOOKING FORM

    Title

    SubTitle
    speaker image

    Content

    Title


    Description

    Download

    Title


    Description

    Download

    Title


    Description


    Download

    copyright © 2024 SAE Media Group


    WHAT IS CPD?

    CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

    ‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

    CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

    Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

    CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

    CPD AND PROFESSIONAL INSTITUTES

    There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

    For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

    CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

    TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

    Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

    ‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

    ‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

    The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

    As a formal provider of CPD certified activities, SAE Media Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

    GLOBAL CPD

    Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

    CPD Certificates

    We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@saemediagroup.com

    Event Title

    Headline

    Text
    Read More

    I would like to speak at an event

    I would like to attend an event

    Group Booking

    Please complete the below form and a member of SAE Media Group’s booking team will be in contact within 24 hours

    I would like to sponsor/exhibit at an event

    SIGN UP OR LOGIN

    Contact SAE Media Group

    UK Office
    Opening Hours: 9.00 - 17.30 (local time)
    SAE Media Group , Ground Floor, India House, 45 Curlew Street, London, SE1 2ND, United Kingdom
    Tel: +44 (0) 20 7827 6000 Fax: +44 (0) 20 7827 6001
    Website: http://www.smgconferences.com Email: events@saemediagroup.com
    Registered in England - SMi Group Ltd trading as SAE Media Group


    Forgotten Password

    Please enter the email address you registered with. We will email you a new password.

    Thank you for visiting our event

    If you would like to receive further information about our events, please fill out the information below.

    By ticking above you are consenting to receive information by email from SAE Media Group.
    Full details of our privacy policy can be found here https://www.smgconferences.com/privacy-legals/privacy-policy/.
    Should you wish to update your contact preferences at any time you can contact us at data.privacy@smgconferences.com.
    Should you wish to be removed from any future mailing lists please click on the following link http://www.smgconferences.com/opt-out

    Fill in your details to download the brochure

    By submitting this form you agree to our privacy policy and consent to receiving communications, you may opt out at any time.