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Microarray Technology : Commercial and Technical Issues
10 February - 11 February 2003
Microarray Technology : Commercial and Technical Issues
“Promises to be an interesting and informative conference” Dr Walter Koch, Roche

Microarray technology allows the simultaneous analysis of thousands of parameters within a single experiment. This exciting technology is revolutionising the way we look at genes and is already proving to be beneficial in the drug discovery process.

Microarray Technology: Commercial and Technical Issues looks at the current and evolving technologies and the applications that can be used with this technology. In addition to this we have experts speaking on a variety of important issues including the manufacturing of arrays and experimental design. This important conference introduces a wide range of scientific speakers presenting the most pressing issues within Microarray Technology whilst providing you with an in-depth analysis of the developments and potential of the biochip market.

Benefits of attending:

  • Meet the key specialists in Microarray Technology presenting on the emerging technologies and recent advances in Microarrays
  • Understand about data capture and quality
  • Learn about new novel technologies
  • Find out about the clinical applications of microarrays
  • Gain insight into the market directions and potential

    A unique opportunity to learn from leading industry experts including:
    Dr Larry Gelbert, Research Scientist & Group Leader, Funtional Genomics, Eli Lilly
    Dr Tarif Awad, Manager, Data Analysis Team, Genomic Collaborations, Affymetrix
    Dr Mischa Reinhardt, Head, Life Science Informatics, Novartis
    Dr Christian Hofmann, Associate Director, Business Development, Roche
    Dr Hilary Clark, Bioinformatics Scientist, Genentech
    Dr Mikhail Soloviev, Head, Protein Assays, Oxford GlycoSciences
    Dr Thomas Joos, Head Biochemistry, Natural and Medical Sciences Institute at the University of Tuebingen presenting on behalf of Luminex
    Dr Alex Chenchik, Director, Gene Cloning, Clontech
    Dr Robert Klein, Vice-President, Technology Development, Deltagen
    Jim George, European Applications Specialist, Amersham Biosciences
    Igor Ivanov, Director, GPC Biotech

  • Conference agenda

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    8:30

    Registration and Coffee

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    9:00

    Chairman's Opening Remarks

    Dr Larry Gelbert

    Dr Larry Gelbert, Research Scientist & Group Leader, Functional Genomics, Eli Lilly

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    9:10

    THE FUTURE AND VISION OF MICROARRAY TECHNOLOGY

    Dr Christian Hofmann

    Dr Christian Hofmann, Associate Director, Business Development, Roche

  • Genetic profiling and prescriptions
  • Disease susceptibility
  • Accurate dose determination
  • Microarrays as diagnostic tools
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    9:40

    THE xMAP SUSPENSION ARRAY

    Dr Thomas Joos

    Dr Thomas Joos, Head Biochemistry, Natural and Medical Sciences Institute at the University of Tuebingen presenting on behalf of, Luminex

  • xMAP technology description
  • Benefits of 3D arrays vs 2D arrays
  • Clinical applications
  • Proteomic applications
  • Genetic screening and profiling
  • Drug discovery and high-throughput screening

    Future developments

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    10:20

    EXPRESSION MICROARRAY TECHNOLOGY

    Dr Mischa Reinhardt

    Dr Mischa Reinhardt, Executive Director, Head, Life Science Informatics, Novartis

  • Collecting information
  • Making experiments comparable
  • Advanced analysis methodologies
  • Integration with our genomic data domains
  • Gaining insight into biological systems
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    11:00

    Morning Coffee

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    11:20

    DO IT YOURSELF ARRAYS

    Dr Roland Green

    Dr Roland Green, Chief Technology Officer & Vice President, Research & Development, NimbleGen Systems

  • Gene expression arrays
  • Genotyping arrays
  • High-density format
  • High-throughput format
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    12:00

    BUILDING A VIABLE PROTEIN MICROARRAY

    Dr Karin Hughes

    Dr Karin Hughes, Vice President, Research & Development, Prolinx

  • The nature of proteins, protein stability
  • Identifying a surface chemistry
  • Selection of capture reagents
  • Pitfalls of printing
  • Choosing a detection method
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    12:40

    Networking Lunch

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    14:00

    RECENT ADVANCES IN MICROARRAY TECHNOLOGY

    Dr Mikhail Soloviev

    Dr Mikhail Soloviev, Head, Protein Assays, Oxford GlycoSciences

  • Protein microarrays at Oxford Glycosciences
  • Linking antibodies to solid support
  • Background issues

    Obtaining quantitative data with affinity arrays

  • Multiplexed affinity assays

    Oxford Glycosciences’ signal displacement assays

  • Protein arrays and mass spectrometry

    The use of peptides vs proteins

  • Peptide capture on an antibody chip
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    14:40

    THE HAPLOTYPE DIRECT – A WORLD FIRST

    Ray Harrison

    Ray Harrison, Chief Business Officer, Point-2-Point Genomics

  • Maternal and Paternal chromosomal haplotype available directly
  • No more algorithm approximation from single SNP analysis
  • Vast reduction in data points, slash numbers for clinical trials
  • HAP discovery and rountine HAP maps for each individual
  • Viral strain differentiation – PAP smear replacement potential
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    15:20

    APPLICATIONS OF MICROARRAY TECHNOLOGY

    Dr Tarif Awad

    Dr Tarif Awad, Senior Scientist, Genomics Collaborations, Affymetrix

  • Expression microarrays: target validation & discovery, toxicology
  • Getting the most out of data
  • GeneChip expression arrays in basic and applied research
  • Target validation study
  • Experimental design, data analysis, data interpretation
  • clock

    16:00

    Chairman’s Closing Remarks followed by Afternoon Tea
    Close of Day One

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    8:30

    Re-registration and Coffee

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    9:00

    Chairman's Opening Remarks

    Dr Robert Klein

    Dr Robert Klein, Vice President, Technology Development, Deltagen

    clock

    9:10

    DESIGNING DNA MICROARRAYS

    Dr Don Montgomery

    Dr Don Montgomery, Chief Technology Officer & Vice-President, Research & Development, NimbleGen Systems

  • CBMX Semiconductor biochip technology
  • MatriXarray system
  • DNA probe design and optimisation
  • Rapid prototyping and customisation
  • Scaleable manufacturing
  • clock

    9:40

    EMERGING TECHNOLOGIES

    Dr Alex Chenchik

    Dr Alex Chenchik, Director, Gene Cloning & Analysis, BDB Clontech

  • Quality of array data and universal calibration standards
  • Normalisation and gene expression databases
  • Cross platform data comparison
  • Perfect probe technology
  • Biases in RNA amplification techniques
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    10:20

    CASE STUDY

    Dr Julian Burke

    Dr Julian Burke, Chief Scientific Officer, Genetix

  • Innovation in research and development
  • Nature of the market
  • Microarraying
  • Scanning
  • Proteomics & cell biology
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    11:00

    Morning Coffee

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    11:20

    IMMUNE DISEASE DRUG TARGET DISCOVERY

    Dr Hilary Clark

    Dr Hilary Clark, Bioinformatics Scientist, Genentech

  • Immune system specific expression as one criterion
  • Panel of microarray experiments on important subsets of immune cells
  • Broad survey of expression in immune cells vs all other tissue categories
  • Identify disease upregulation in immune cell types
  • Focus by considering known immune gene characteristics
  • Establishing a pipeline for immune gene assessment
  • clock

    12:00

    RESEARCH APPLICATIONS

    Douglas Lane

    Douglas Lane, CEO, ViaLogy

  • Data analysis
  • Data capture and bioinformatics
  • Variability
  • Data quality
  • Sample preparation and amplification
  • Standardisation between experiments
  • clock

    12:40

    Networking Lunch

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    14:00

    HIGH PERFORMANCE IN MICROARRAY EXPERIMENTS

    Jim George

    Jim George, European Applications Specialist, Amersham Biosciences

  • Customised and prearrayed slides: overview of the Lucidea platform and CodeLink platform
  • Quality control and its benefits
  • Diagnostics, what’s next?
  • clock

    14:40

    PATENTING AND LICENSING ISSUES

    Sarah Turner

    Sarah Turner, Senior Solicitor, Lovells

  • The importance of intellectual property
  • Patent strategies
  • Patent conflicts
  • Freedom to operate
  • Research tools
  • Licensing strategies

    Practical steps to protecting your investment

  • clock

    15:20

    Afternoon Tea

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    15:40

    CURRENT MARKET TRENDS

    Andreas Schafer

    Andreas Schafer, Associate Director, Qiagen

  • Size and growth of the market
  • Division of the market
  • Technological shifts and advances
  • The next generation arrays
  • Market shares
  • Market opportunities
  • clock

    16:20

    APPLICATIONS IN DRUG DISCOVERY

    Igor Ivanoff

    Igor Ivanoff, Director, GPC Biotech

  • Technological aspect: industrialisation and high throughput
  • Experimental design: concentrations, time, mutants
  • Statistical aspects of biological meaning
  • Validation using functional assays
  • clock

    17:00

    Chairman's Closing Remarks and Close of Conference

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    London EC1N 8HN
    United Kingdom

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