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Impact of New Technologies on Pharmacoeconomics
8 November - 9 November 1999
Impact of New Technologies on Pharmacoeconomics
Pharmacoeconomics is increasingly important in today’s competitive pharmaceutical market, particularly as recent regulatory changes require more pharmacoeconomic data. This conference will explore the recent advances in pharmacoeconomic analysis in the wake of rapid advances in technology such as proteomics, genomics and information technology. It will show how these impact on the drug discovery process and pharmacoeconomic analysis. The speakers will use case studies to demonstrate how to integrate these changes into your own health economic department.

As a senior industry executive, you will be aware of the importance of pharmacoeconomics. We would therefore like to invite you to register for SAE Media Group’s ‘Impact of New Technologies on Pharmacoeconomics’. As you will see from the brochure, key speakers include representatives from the NHS and leading pharmaceuticals companies.

The conference offers you the opportunity to network with key pharma industry experts. Attend to discover the rapid advances being made in reducing drug discovery times and to learn about the future of pharmacoeconomic analysis.

‘Impact of New Technologies on Pharmacoeconomics’ is organised and produced by SAE Media Group: we specialise in providing senior executives with timely, strategic and focused business information. SAE Media Group conferences are leading-edge business events offering delegates the opportunity to meet senior industry and government figures and seek their advice and opinions.

Conference agenda

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9:00

Registration

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9:30

Introductions

  • Review of participants past experience and expectations from the day. Review of the agenda for remaining sessions.
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    10:00

    The Economists’ Approach: Balancing Costs with Outcomes

  • This session will provide an overview of health economics approaches and the main types of pharmacoeconomic study carried out (Cost Minimisation, Cost Effectiveness, Cost Utility, Cost Benefit).
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    10:30

    Understanding the Economists’ Definition of Costs

  • This session will focus on the ways in which economists define and measure costs. It will include a detailed discussion of the principles of costing and touch on a range of issues that affect the potential costs of individual interventions, e.g. marginal cost, opportunity cost, friction costs.
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    11:00

    Review and Questions

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    11:15

    Coffee

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    11:30

    Costing Case Study

  • Using a simple example of a new intervention, participants will work in groups to examine the potential costs associated with the existing and new interventions to be assessed.
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    12:15

    Review of Case Study and Questions

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    12:30

    Lunch

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    14:00

    Measuring Outcomes.

  • This session will review methods used to assess outcomes, required for carrying out each main type of study including: health and ADL measures; QuALYs; techniques for eliciting willingness to pay.
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    14:45

    Questions and Discussion

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    15:00

    What do the Regulators Want?

  • This session will review: the requirements of countries where explicit pharmacoeconomic evaluation has been added to the assessment and approval of new drugs; the use made of impact models for marketing study results to health purchasers and providers
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    15:30

    Tea

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    15:45

    Carrying out a Pharmacoeconomic Study

  • Issues of Timing and Data Collection. This session will examine: the advantages and potential difficulties of undertaking a pharmacoeconomic study at different points in the development and marketing process; the use of modelling techniques at an early stage of the evaluation process, prior to detailed data collection.
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    16:30

    Questions and Comments

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    16:45

    Review of the day and Unanswered Questions

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    8:30

    Registration and Coffee

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    9:00

    Chairman's Opening Remarks

    Prof Nick Bosanquet

    Prof Nick Bosanquet, Professor of Health Policy, Imperial College

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    9:10

    UPDATE ON PHARMACOECONOMICS

    Dr Koen Torfs

    Dr Koen Torfs, Director Global Health Economics, Janssen Pharmaceutica

  • The changing role of pharmacoeconomic analysis within the Pharma industry
  • Patient empowerment and outcomes research
  • New technologies increasing the pace of drug discovery
  • New technologies increasing the pace of drug discovery
  • The advantages of IT in reducing the costs of research
  • Future directions for pharmacoeconomics
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    9:40

    RELEVANCE OF PHARMACOECONOMICS TO THE PHARMA INDUSTRY

    Dr Jean Paul Gagnon

    Dr Jean Paul Gagnon, Director, Health Policy, Hoechst Marion Roussel

  • Regulatory changes affecting the use of pharmacoeconomic analysis
  • Uses of value analyses
  • Role of pharmacoeconomics in a pharmaceutical company
  • Issues in the use of pharmacoeconomic analysis
  • How accurate are pharmacoeconomic trials?
  • Relevance of outcomes research to industry
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    10:20

    THE UK QUALITY AGENDA AND IMPLICATIONS FOR INDUSTRY

    Charles Dobson

    Charles Dobson, Pharmacy and Prescribing Branch, NHS Executive

  • NICE and the requirement for pharmacoeconomic analysis
  • Impact of generic competition on pricing issues
  • Quality of life drugs and government policy
  • Value of pharmacoeconomics studies under new regulations
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    11:00

    Morning Coffee

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    11:20

    LOGISTICS OF A PHARMACOECONOMIC STUDY

    Dr Anne Marciniak

    Dr Anne Marciniak, Outcomes Research Manager, Pfizer

  • Identifying the size of the therapeutic market
  • Potential bottlenecks to slow down the drug discovery process
  • How much would patients be willing to pay?
  • Requirements of regulatory bodies for specific therapeutics
  • Ensuring pharmacoeconomic requirements are factored into clinical trials
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    12:00

    PHARMACOECONOMICS AND THE REAL WORLD

    Dr Tony Lockett

    Dr Tony Lockett, Associate Director, Clinical Research, Covance Health Economy and Outcomes Services

  • Real world variables as opposed to clinical settings
  • Patient compliance
  • Trial population size
  • Quality of life vs Quality of health measurements
  • Following up on outcomes
  • Clinical analysis and submission of data to the public arena
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    12:40

    Lunch

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    14:00

    PATIENT COMPLIANCE AND PHARMACOECONOMICS

    Dr Dyfrig Hughes

    Dr Dyfrig Hughes, Research Fellow, University of Liverpool

  • Improving outcomes data by establishing effectiveness
  • Effectiveness vs Efficacy: how well is effectiveness established in clinical trials?
  • Pharmacokinetic aspects of non-compliance
  • Impact of non compliance on effectiveness of drugs
  • Modelling non-compliance
  • Implications of non-compliance modelling for pharmacoeconomic analysis
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    14:40

    PRIORITISING HEALTH ECONOMIC WORKLOAD

    John Kerrigan

    John Kerrigan, Health Economics Manager, Hoffmann-La Roche

  • A review of priority setting tools used by industry Health Economists
  • The benefits of a systematic priority setting process
  • The interaction of an appropriate plan with other in-company functions.
  • The ‘ Priority Calculator’ - making priority setting a routine process and transparent for all
  • Case studies: priorities within companies
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    15:20

    Afternoon Tea

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    15:40

    INCREASING IMPORTANCE OF QUALITY OF LIFE

    Catherine Morris

    Catherine Morris, Market Development, Team Consulting

  • Evidence-based consumer choice in the pharmaceutical market
  • Quality of life issues vs medical outcomes
  • Incorporating consumer perspectives in device design
  • Medical market segmentation
  • Changing influence of the value chain
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    16:20

    QUALITY OF LIFE STUDIES

    Dennis D Gagnon

    Dennis D Gagnon, Assistant Director, ICOM Health Economics, Johnson and Johnson

  • Basic Structure of a QOL study
  • Types of QOL instruments:Symptom checklist, Condition-specific, Generic, Utility
  • QOL as a secondary efficacy endpoint?
  • Advances in the technology of measuring utility
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    17:00

    Chairman's Closing Remarks and Close of Day One

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    8:30

    Re-registration and coffee

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    9:10

    Chairman's Opening Remarks

    Dr Richard Wyse

    Dr Richard Wyse, Chairman, Economic Healthcare Associates

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    9:10

    IMPACT ON MARKETING FOR PHARMA COMPANIES

    Edward Gudaitis

    Edward Gudaitis, Director, Business Policy and Market Access, Hoffmann-La Roche

  • Altering marketing strategies to take into account pharmacoeconomic studies
  • Pharmacoeconomics as a pre-marketing tool
  • Payers as a marketing target
  • Selling to physicians using pharmacoeconomic information
  • Quality of life drugs
  • Information influencing patient choice - ‘Consumer pharmacoeconomics’
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    9:40

    INFORMATION TECHNOLOGY AND ITS ROLE IN PHARMACOECONOMICS

    Dr Jeffrey Green

    Dr Jeffrey Green, President and Chief Executive Officer, DataTRAK

  • Difficulties in obtaining long term outcomes information
  • Keeping track of demographics
  • Sharing data on a global scale
  • Increasing the accessibility of data: Data mining
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    10:20

    IT AND COST REDUCTION

    Dr Peter Hoffman

    Dr Peter Hoffman, Senior Vice President and Chief Medical Officer, PharMark

  • IT and managed healthcare costs
  • Software intelligence and predicting outcomes
  • Using IT to determine improved health outcomes with respect to cost
  • Efficacy vs side effect profile
  • High cost vs low cost
  • Rationalisation of clinical process costs in the pharma industry
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    11:00

    Morning Coffee

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    11:20

    INCREASING COSTS OF DRUG DISCOVERY

    Dr Hannah Kettler

    Dr Hannah Kettler, Industrial Economist, Office of Health Economics,

  • Pitfalls and advantages of predicting future estimates
  • Increased time between lead candidate identification and regulatory approval
  • Increasing regulation requirements increases costs
  • Shifts in focus from acute to chronic disorders and the corresponding increase in costs
  • Impact of new technology and the reorganisation of R and D on costs
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    12:00

    REDUCING THE COSTS OF DRUG DISCOVERY

    Brian Lovatt

    Brian Lovatt, Director, Vision Health

  • Timing of ClinicoEconomics studies: are these feasible before the clinical trial stage?
  • Anticipation of bottlenecks
  • Planning kill off times for drug candidates
  • Team playing between research and pharmacoeconomics departments
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    12:40

    Lunch

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    14:00

    QUICKENING THE PACE OF DRUG DISCOVERY

    Dr Deval Lashkari

    Dr Deval Lashkari, Vice President, Marketing and Business Development, Genometrix

  • Identification of responders for clinical trial enrolment
  • Predicting adverse responses to drugs
  • Identification of prospective toxicity problems
  • Reduction in time from discovery to market place
  • Personalised drugs and preventative medicine
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    14:40

    BIOTECHNOLOGY SHAPING THE DEMAND FOR AND FOCUS OF PHARMACOECONOMIC DATA

    Dr M Haim Erder

    Dr M Haim Erder, Department Head, Health Economics, Amgen

  • Why do biotechnology products shape the demand, conduct, and dissemination of pharmacoeconomic data
  • Neupogen and its clinical outcomes
  • Neupogen changing demand for pharmacoeconomic data from cost minimization to cost benefit.
  • The impact of pharmacoeconomic data on Neupogen utilisation
  • Lessons and recommendations
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    15:20

    Afternoon Tea

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    15:40

    THE FUTURE OF HEALTHCARE

    Michael Kranda

    Michael Kranda, Chief Executive Officer, Oxford GlycoSciences

  • Prospects with proteomics, Individual medicine, the future of healthcare?
  • Prediction of side effect profile, Identification of therapeutic targets
  • Rational design of therapeutic molecules
  • Increasing the speed of identification of lead candidates
  • Early establishment of toxicity profile and impact
  • Pharmacoeconomics
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    16:20

    FUTURE OF PHARMACOECONOMIC ANALYSIS

    Dr Lisa Kennedy,

    Dr Lisa Kennedy,, Scientific Director for Europe, The Lewin Group

  • Potential for individually tailored drugs: ‘Boutique drugs’
  • ‘Boutique’ drugs and their cost effectiveness
  • Accelerating identification and optimisation of candidates
  • Reducing the length and size of clinical trials by identification of correct patient groups
  • Clinical markers for monitoring patient progress
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    17:00

    Chairman's Closing Remarks and Close of Conference

    Workshops

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    WHAT IS CPD?

    CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

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