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Cell Culture

Taking an international expert speaking faculty join us at SAE Media Group's Cell Culture conference due to take place on the 3 & 4 July 2013 in central London.


Cell culture is set to see huge increases in growth including the recent advances in techniques such as 3D cell culture. The cell culture market is set to be worth £4.5 billion by 2020 driven by advances in pharma and biotech. Over the two day conference delegates will be exposed to leading decision makers in a range Cell Culture related fields from Europe and the States, listen to our keynote speakers on day one speak about the latest data coming back from culture techniques being used on the International Space Station.
 

Day one will focus on the recent advances in 3D cell culture. Case studies will demonstrate how this method is providing highly physiologically accurate preclinical data and current approaches for culture in relevant diseases.
 

Day two's speaking faculty will focus on cell culture process development and cell line development including the use of high throughput technologies.
 

Our 3-day event, formed of two half day post-conference workshops and a two-day conference will provide useful insights into the latest developments within cell culture.
 

FEATURED SPEAKERS

Anthony Davies

Anthony Davies

Director of the High Content Facility, Trinity College Dublin
Berthold Boedeker

Berthold Boedeker

Chief Scientist, Bayer
Kalpana Nayyar

Kalpana Nayyar

Scientist I, MedImmune
Timothy Hammond

Timothy Hammond

Doctor, Investigator, Durham Veterans Affairs Medical Center, (Principle Investigator – NASA)

Anthony Davies

Director of the High Content Facility, Trinity College Dublin
Anthony Davies

Berthold Boedeker

Chief Scientist, Bayer
Berthold Boedeker

Fozia Noor

Biochemical Engineering, Saarland University
Fozia Noor

Frank Baganz

Senior Lecturer, University College London
Frank Baganz

Gareth Griffiths

Director, Imagen Biotech
Gareth  Griffiths

Jean Albrengues

Fellow, ICRAN
Jean  Albrengues

Jens Kelm

CSO and Co-founder, , Insphero A G
Jens Kelm

Jens Traenkle

Head of PAT Biotechnology, Bayer
Jens Traenkle

John Haycock

Professor of Bioengineering, University Of Sheffield
John Haycock

Kalpana Nayyar

Scientist I, MedImmune
Kalpana Nayyar

Karen Coopman

Lecturer, Loughborough University
Karen Coopman

Katharine Cain

Senior Scientist, UCB
Katharine Cain

Magnus Ingelman-Sundberg

Professor and Section Head Department of Physiology and Pharmacology, Karolinska Institute
Magnus Ingelman-Sundberg

Olivier Pardo

Team Leader, Imperial College London
Olivier Pardo

Timothy Hammond

Doctor, Investigator, Durham Veterans Affairs Medical Center, (Principle Investigator – NASA)
Timothy Hammond

Conference agenda

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12:30

Registration & Coffee

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13:00

Welcome & Introductions

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13:10

An overview of the main application areas of 3D assay and cell culture technologies

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13:45

An appraisal of all the currently technologies and their key advantages

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14:45

Afternoon refreshments

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15:00

Presentation of research data from a few selected studies using 3D assay technologies

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15:45

Q&A and group discussion

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16:30

Close of workshop

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8:30

Registration & Coffee

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9:00

Chairman's Opening Remarks

Anthony Davies

Anthony Davies, Director of the High Content Facility, Trinity College Dublin

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9:10

Studies of metabolism in the unique culture environment of microgravity in space

Timothy Hammond

Timothy Hammond, Doctor, Investigator, Durham Veterans Affairs Medical Center, (Principle Investigator – NASA)

  • Unique opportunities afforded by space flight
  • Low shear suspension culture
  • Reduced gravity dependent convection for volatile gas signalling
  • The unique pathway analysis determined in space
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    9:50

    Advances in technologies and new approaches to 3D cell biology in the SBS micro-plate format

    Anthony Davies

    Anthony Davies, Director of the High Content Facility, Trinity College Dublin

  • What are the options in terms of current technologies for the in vitro study of cell in 3 dimensions.
  • What are their limitations
  • A description of a completely novel 3D cell culture system developed
  • Ease and convenience that this technology offers in the automated culture of cells in 3D
  • Ease in subsequent analysis by means of biochemical, imaging and Raman assay technologies
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    10:30

    Morning Coffee

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    11:00

    Discriminating drug effects in multi-cell type 3D cell culture models

    Jens Kelm

    Jens Kelm, CSO and Co-founder, , Insphero A G

  • Design of heterotypic microtissue models for efficacy and safety testing
  • Use of intracellular fluorescent reporter systems to discriminate drug effects in 3D models
  • Use of secreted luminescence reporter systems in 3D models
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    11:40

    3 dimensional hepatic models for prediction of human drug metabolism and toxicity

    Magnus Ingelman-Sundberg

    Magnus Ingelman-Sundberg, Professor and Section Head Department of Physiology and Pharmacology, Karolinska Institute

  • Comparison between different systems for in vitro cultivation of liver cells in 3D for long period of times
  • Phenotype differences of liver cells in 2D vs 3D models
  • Utilization of 3D models for identification of hepatic biomarkers for drug hepatotoxicity
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    12:20

    Networking Lunch

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    13:50

    The power of three. 2D Vs 3D Vs cancer stem cell assays. What can they tell us?

    Gareth  Griffiths

    Gareth Griffiths , Director, Imagen Biotech

  • Focus on the advancement of a new range of 3D assays and compare the 2D environment versus 3D. Do drugs really behave differently?
  • Cancer stem cell assays using mammosphere and neurosphere formation assays
  • All 3 of these assays have been used to screen an anticancer compound library
  • Case study: Differences between these assays using breat and glioblastoma lines
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    14:30

    Studying cell invasiveness using complex 2D and 3D culture assays and zebrafish models

    Olivier Pardo

    Olivier Pardo, Team Leader, Imperial College London

  • Different in vitro experimental models developed in lab to assess various aspects of the metastatic process
  • Attention will be drawn to limitations of these techniques
  • Zebrafish models are powerful tool to perform high-content analysis of metastasis and tumour growth
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    15:10

    3D biological screening to identify compound that block matrix remodelling by Carcinoma associated fibroblasts

    Jean  Albrengues

    Jean Albrengues, Fellow, ICRAN

  • Carcinoma associated fibroblasts.
  • Matrix remodelling.
  • Signaling
  • clock

    16:00

    Chairman’s Closing Remarks and Close of Day One and Afternoon Tea

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    8:30

    Registration & Coffee

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    9:00

    Chairman's Opening Remarks

    Anthony Davies

    Anthony Davies, Director of the High Content Facility, Trinity College Dublin

    clock

    9:10

    The renaissance of perfusion fermentation

    Berthold Boedeker

    Berthold Boedeker, Chief Scientist, Bayer

  • The classical perfusion culture
  • Continuous processing of biologics
  • Perfusion for high cell density inoculation and closed seed expansion
  • clock

    9:50

    Cell line development: Improvements through modifications at an early stage

    Katharine Cain

    Katharine Cain, Senior Scientist, UCB

  • High through-put technologies have enabled more efficient screening but modifications in the early stages of cell line generation
  • A number of approaches including the use of engineered cell lines, chromatin modifying elements, and the overexpression of “helper” proteins have been examined
  • UCB case study on data that has helped understand our cell line development proces
  • clock

    10:30

    Morning Coffee

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    11:00

    3D organotypic cultures of hepatic cells as an in vitro tool for toxicity assessment

    Fozia Noor

    Fozia Noor, Biochemical Engineering, Saarland University

  • 3D spheroid cultures
  • 3D hollow fibre bioreactors
  • 3D cultivation of liver cells (primary and cell lines)
  • clock

    11:40

    Automated online analytics as a PAT application for bioprocesses

    Jens Traenkle

    Jens Traenkle, Head of PAT Biotechnology, Bayer

  • Conventional lab analytics and IPC are often a bottleneck in multiple bioreactor setups, usually employed in DoE
  • Automated sampling and analysis will help releasing this bottleneck
  • Automated sampling system, bringing standard laboratory analyzers to the process allowing high data densities and also feedback control
  • 24/7 unattended operation of the BaychroMAT sampling system, fed-batch, long-term perfusion cultures and it’s application in a feedback control strategy
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    12:20

    Networking Lunch

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    13:50

    Accelerating cell culture process development by use of miniature bioreactor technologies

    Frank Baganz

    Frank Baganz, Senior Lecturer, University College London

  • Need for greater speed led to development of miniature and parallel bioreactor systems
  • Focus on shaken microwells and  miniature stirred bioreactors
  • Engineering characterisation in terms of power input, liquid mixing and oxygen transfer
  • Examples for scale translation from miniature to bench scale bioreactors
  • clock

    14:30

    Implementation of the Octet for Rapid High Throughput Antibody Quantitation

    Kalpana Nayyar

    Kalpana Nayyar, Scientist I, MedImmune

  • Validation of the Octet to current method
  • Regeneration of biosensors
  • Automation of the process for rapid analysis
  • clock

    15:10

    Evaluating the effect of standard cryopreservation protocols on long-term cell survival and quality

    Karen Coopman

    Karen Coopman, Lecturer, Loughborough University

  • Cell preservation will be a critical part of the manufacturing process for any allogeneic cellular therapy enabling storage and transport from manufacturing facility to bedside.
  • Cells are typically cryopreserved in a DMSO-containing freezing solution despite reports that DMSO can detrimentally affect cell quality, particularly at temperatures above 0°C. 
  • Using an understanding of industrial-scale processing constraints; we are currently defining a realistic processing window which will not negatively impact cell survival or quality. 
  • clock

    16:00

    Chairman’s Closing Remarks and Close of Day Two and Afternoon Tea


    Professor and Section Head Department of Physiology and Pharmacology
    Karolinska Institute
    Senior Lecturer
    University College London
    Senior Scientist
    UCB
    Chief Scientist
    Bayer
    Scientist I
    MedImmune
    Team Leader
    Imperial College London
    Professor of Bioengineering
    University Of Sheffield
    Head of PAT Biotechnology
    Bayer
    Director
    Imagen Biotech
    Doctor, Investigator
    Durham Veterans Affairs Medical Center, (Principle Investigator – NASA)
    Fellow
    ICRAN
    Director of the High Content Facility
    Trinity College Dublin
    Biochemical Engineering
    Saarland University
    Lecturer
    Loughborough University
    CSO and Co-founder,
    Insphero A G

    Copthorne Tara Hotel

    Scarsdale Place
    Kensington
    London W8 5SR
    United Kingdom

    Copthorne Tara Hotel

    The Copthorne Tara Hotel London Kensington is an elegant contemporary four-star hotel in prestigious Kensington, located just a two minutes walk from High Street Kensington underground station, making exploring easy. The hotel offers well-appointed and comfortable guest rooms combining Standard, Superior and Club accommodation. Club rooms offer iconic views over the city and include Club Lounge access for complimentary breakfast and refreshments. Guests can sample the authentic Singaporean, Malaysian and Chinese cuisine at Bugis Street, traditional pub fare at the Brasserie Restaurant & Bar or relax with a delicious drink at West8 Cocktail Lounge & Bar.

    The Copthorne Tara Hotel boasts 745 square meters of flexible meeting space, consisting of the Shannon Suite and the Liffey Suite, ideal for hosting conferences, weddings and social events. Facilities include access to the business centre 24 hours a day, fully equipped fitness room, gift shop, theatre desk and Bureau de Change. With ample onsite parking outside the London congestion charge zone and excellent transport links via Heathrow Airport, the hotel is the perfect location for business or leisure stays. The hotel is within close proximity to the shops of High Street Kensington, Knightsbridge and Westfield London, Olympia Conference Centre, Royal Albert Hall, Kensington Palace and Hyde Park.

     

    HOTEL BOOKING FORM

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    WHAT IS CPD?

    CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

    ‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

    CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

    Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

    CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

    CPD AND PROFESSIONAL INSTITUTES

    There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

    For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

    CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

    TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

    Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

    ‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

    ‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

    The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

    As a formal provider of CPD certified activities, SAE Media Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

    GLOBAL CPD

    Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

    CPD Certificates

    We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@saemediagroup.com

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