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Controlled Release Delivery
21 March - 22 March 2018
Controlled Release Delivery

SAE Media Group announces the 15th Annual Controlled Release Delivery Conference in London on March 21st - 22nd 2018. As physicians continue to request drugs which have a reduced dosage requirement, higher action times and assist in simplifying treatment schedules for patients, the focus of the pharmaceutical industry is continually moving towards innovative controlled release delivery technologies, which improve drug transport to the target.

This year’s event will bring together industry experts from pharmaceutical companies, regulatory agencies and biotechs to analyze and evaluate the latest advancements in Controlled Release Delivery, including the addressing formulation challenges of Abuse-Deterrent and oral lipid based Formulations, targeting controlled release delivery with Polymer Nanoparticles and how to overcome the additional challenges in controlled release delivery for pediatric medicine.

With the Oral Controlled Release Drug Delivery Technology Market expected to be worth $ 50,000 Mn in revenues by 2027,* the event this year will have a particular focus on Oral Controlled Release Delivery technologies and will also examine the strategies, which pharmaceutical companies are using formulate new Controlled release drugs and scaling up from the batch process for commercial applications.

 *https://www.futuremarketinsights.com/reports/oral-controlled-release-drug-delivery-technology-market

VIP Treatment:
To all the SAE Media Group delegates choosing to stay at the Copthorne Tara Hotel in February and March, we will offer an upgrade to a superior room and welcome drink voucher
 

sponsors

Conference agenda

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8:30

Registration & Coffee

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9:00

Chairman's Opening Remarks

Joël Richard, Senior Vice President, Peptides Development, IPSEN

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9:10

Advances in Non-Invasive Routes of Administration of Peptides: Focus on Successful Oral Technologies Progressing in the Clinic

Joël Richard, Senior Vice President, Peptides Development, IPSEN

  • Peptide Delivery Landscape and Importance of Non-Invasive Routes of Administration
  • Oral Peptide Delivery: Strong Expectations and Opportunities from the Market
  • Key Oral Peptide Formulation Excipients
  • Oral Peptide Technologies Progressed in the Clinic
  • Lessons Learnt from Clinical Studies
  • Future Challenges & Prospects
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    9:50

    Targeted peptide nanofibers for brain diseases and tumours

    Katerina Lalatsa, Senior Lecturer in Pharmaceutics and Drug Delivery, University Of Portsmouth

  • Targeted Biologicals and Delivery Systems for Brain Diseases and Tumours
  • Peptide Nanofibers  in Drug Delivery
  • Targeted Nanofibers for brain diseases and tumours
     
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    10:30

    Morning Coffee

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    11:00

    How-to Use Oral Drug Delivery Technology Innovatively

    Jin-Wang Lai

    Jin-Wang Lai, Senior Director Pharmaceutical Development, Adare Pharmaceuticals

  • Focus on the use of oral pulsatile release design as a way to leverage chronotherapy, mimic bid or tid dosing, create a challenge to generic competition
  • Timed delivery of two different active ingredients and provide both quick onset of action and quick termination of action
  • Target delivery to a specific GI site of action
  • Adare Proprietary Pulsatile Release Technology featured case studies to be presented.
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    11:40

    Impact of the current EU Guideline EMA/CPMP/EWP/280/96/Corr 1 on the pharmacokinetic and clinical evaluation of modified release dosage forms of generic drug products

    Pavel Farkas, Senior Director Biopharmaceutics Clinical Development, PLIVA

  • Purposes of the guideline and general considerations
  • Types of oral modified release products from the biopharmaceutics perspective
  • General rules for types of required bioequivalence studies
  • Primary PK parameters for demonstration of bioequivalence and their evaluation in single-dose and multiple-dose studies
  • Case-by-case approach
     
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    12:20

    Networking Lunch

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    13:30

    Oral lipid based formulations, general advantages, challenges and taste masking approaches

    Ezequiel Monteagudo, Platform Expert, GSK

  • Advantages of lipid based oral formulations for poorly soluble compounds 
  • Taste masking challenges derived from APIs and formulations
  • Latest technologies applied to taste masking evaluation
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    14:10

    Multi phasic oral drug delivery – in-vivo opportunities and challenges

    Howard Stevens

    Howard Stevens, Emeritus Professor, University of Strathclyde

  • What mechanisms define complex oral drug delivery profiles?
  • The release of drug from complex oral drug delivery systems should be entirely independent of patient factors such as pH and GI motility. 
  • Case study:  OralogiKTM - an erosion based technology
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    14:50

    Afternoon Tea

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    15:20

    Abuse deterrent formulation technologies - requirements, development and testing

    Carmen Stomberg, Head of Laboratory Innovation Unit Devices & Technologies - Research, Gruenenthal Group

  • Development rational for Abuse deterrent formulations
  • Formulation approaches and Technologies for Abuse deterrent formulations
  • In-vitro characterization and how to use data from those testing
  • Clinical studies with ADF: bioequivalence and abuse liability
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    16:40

    Chairman’s Closing Remarks and Close of Day One

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    8:30

    Registration & Coffee

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    9:00

    Chairman's Opening Remarks

    Howard Stevens

    Howard Stevens, Emeritus Professor, University of Strathclyde

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    9:10

    Emergence of 3D printed dosage forms: opportunities and challenges

    Mohamed Albed Alhnan, Senior Lecturer in Pharmaceutics, University Of Central Lancashire

  • Current solutions for personalizing dose and Potential of 3D printing
  • Current 3D printing technologies & dosage forms
  • FDM 3D printing of tablets and capsules
  • Overcoming the technical and regulatory challenges with 3D printed medicines.
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    9:50

    Taste masking & Controlled Release Approaches

    Barry Friend, Senior Technical Manager, Colorcon Ltd

  • Industrial Perspective/Trend on Paediatric oral formulation development
  • Taste masking using Barrier Membrane & Ion Exchange Resign Approaches
  • Is there value for Controlled Release Oral for Paediatric formulation?
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    10:30

    Morning Coffee

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    11:00

    The Impact of Variability of GI Parameters on Design of Functional Film Coats

    David Elder

    David Elder, Principal Consultant, David P Elder Consultancy

  • Overview of role of aqueous film coating
  • New understanding of variability of GI tract physicochemical parameters 
  • Impact on delayed release product development targeting (i) duodenum release, (ii) colonic release
  • Impact on controlled release product development
  • Conclusions
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    11:40

    The Guardian™ Technology – Injection Molding of Tablets

    Karsten Lindhardt, CSO, Head R&D, Egalet Corp

  • What Differentiates Injection Molding from other Tablet Technologies
  • Controlled, Delayed and Sophisticated Precision Drug Release
  • Arymo®ER – The First Injection Molded Tablet on the Market
  • Future Perspectives of Injection Molding Tablets

     

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    12:20

    Networking Lunch

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    13:30

    Nanocin™ a novel polymer-based platform for nanomedicine

    Liam Good, Director, Tecrea Ltd

  • Introduction to Nanocin technology
  • Mechanisms of nanoparticle formation, cell delivery and release
  • Examples of drug:nanocin nanoparticles
  • Overview of Tecrea’s projects and partnerships
     
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    14:10

    Lipid-composite microparticles from expanding, liquid-CO2 technology: advantages, challenges and areas of application

    Pierandrea Esposito, Cofounder and Associate Director, SiTec PharmaBio

  • Liquid-CO2 expansion applied to cryospraying technology 
  • Combining amphiphilic excipients to control microparticles drug product performance
  • Liq-CO2 Cryospraying Technology applications for oral and topical delivery
  • Use of Carbon-dioxide technologies as integrated line for natural products: extraction, fractionation, micronization
     
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    14:50

    Afternoon Tea

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    15:20

    Nanomerics’ Molecular Envelope Technology

    Ijeoma Uchegbu, Chief Scientific Officer, Nanomerics Ltd.

  • Analysis of Nanomerics’ Molecular Envelope Technology as an emerging technology (Winner of First prize in the Royal Society of Chemistry’s Emerging Technologies 2017 competition in the Health category)
  • Developing differentiated medicines with nanotechnology - common mistakes and pitfalls
  • Core issues to enable differentiation: chemical and manufacturing controls on excipient, drug loading, colloidal stability, unique biological properties
  • Case studies involving medicines under development
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    16:00

    Peptide hydrogel platform for tissue repair and drug delivery

    Aline Miller

    Aline Miller, Co-Founder and Research Director, PeptiGelDesign Technologies

  • Bio-inspired hydrogels for control release
  • Simple drug delivery system for injectables and sprayables
  • Complex drug delivery system for multi-profile drugs elution rate
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    16:40

    Chairman’s Closing Remarks and Close of Day Two

    Sponsors and Exhibitors

    Supporters

    Dr. Lindhardt Interview

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    Past Attendee List - Controlled Release Delivery 2017

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    Sponsors and Exhibitors


    Adare Pharmaceuticals

    Sponsors and Exhibitors
    http://www.AdarePharma.com

    Adare is a global specialty pharmaceutical company inspired to create new possibilities for patients whose treatment needs are not fully addressed by current medications. With a growing pipeline, focused R&D efforts, and global manufacturing capabilities, Adare is actively exploring value creation through development and expansion across therapeutic areas. Adare has a proven track record from concept through commercialization that can help you overcome formulation challenges and add valuable IP to your current and future products. Formulation challenges? Experience a partnership focused on the needs of patients and your company’s goals, contact us at BusDevROW@adarepharma.com


    Precision NanoSystems

    Sponsors and Exhibitors
    http://www.precisionnanosystems.com/

    Precision NanoSystems Inc (PNI) creates innovative solutions for the discovery, development and manufacture of novel nanoparticles for use as medicines and in medical research. PNI’s proprietary NanoAssemblr Platform enables the rapid, reproducible, and scalable manufacture of next generation nanoparticle formulations for the targeted delivery of therapeutic and diagnostic agents to cells and tissues in the body. PNI provides instruments, reagents and services to life sciences researchers, including pharmaceutical companies, and builds strategic collaborations to revolutionize healthcare through nanotechnology.

    Media Partners


    Labsave

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    Labsave is the leading savings website for Laboratory Equipment and Lab Supplies. We work closely with the top suppliers in the world to bring you the best products at the most competitive prices. We are constantly striving to secure the biggest and most exclusive offers that you won’t find anywhere else! http://www.labsave.com/


    Pharma Journalist

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    Pharma Journalist is a product of Kellen Media. Pharma Journalist is one of the leading website covering the need of global Pharmaceutical Industry. Articles like latest news, trends, analysis, market report, press releases, whitepapers, case studies, etc. published on pharmajournalist.com helps Industry professionals and decision makers to stay on the top of this fast-paced industry. Pharma Journalist aims of providing fast and informative articles to its readers and subscribers.


    Absave

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    http://www.absave.com

    Absave.com is the leading savings website for Antibodies and Immunological Products. Search our extensive database of Antibodies, Kits, Proteins & Peptides, Reagents, etc. to find the best savings!


    Inderscience Publishers

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    http://www.inderscience.com

    Inderscience is a dynamic, leading, independent journal publisher. The company disseminates the latest research across the broad fields of science, engineering and technology; management, public and business administration; environment, ecological economics and sustainable development; computing, ICT and internet/web services, and related areas. Inderscience offers over 35 years' experience in publishing and has succeeded in building a substantial collection approaching 400 high-quality peer-reviewed international research journals in both online and print formats. We offer a variety of ways to keep up-to-date with the latest published leading-edge research while our online collection represents a fully-searchable digital archive of around 60,000 articles.


    ONdrugDelivery Magazine

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    http://ondrugdelivery.com

    ONdrugDelivery provides 30,000 readers throughout global pharma/biopharma, with the latest, most pertinent industry information and intelligence about the drug delivery-related ideas, technologies, services and products the sector is developing. Established in 2004, and trusted throughout the industry for its high quality contributions from leading drug delivery experts, ONdrugDelivery is a must for pharma / biotech industry professionals who need to know what’s going on in drug delivery. Subscribe online today to the print or free digital edition: www.ondrugdelivery.com/subscribe.


    Select Science

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    http://www.selectscience.net/

    SelectScience is an independent, online information resource for the worldwide scientific community, and the home of trusted information for laboratory scientists. Discover impartial, expert opinion and trusted reviews about latest laboratory equipment and techniques; plus videos, application notes and science news from around the world. Become a member for free today.


    Farmavita

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    FarmavitaR+ is the professional network of experts and service providers. Network is gathering local consultants from 90 countries in Europe, Asia, North America, Latin America, Australia and Africa. Management of international, multi-centre projects is our core competence. FarmavitaR+ is providing solutions related to pharmaceutical, medical device, food supplement and cosmetic products. Scope of services is related to solutions for product development, quality assurance, clinical trials, product registration, portfolio analysis, lifecycle management, vigilance/risk management, pricing/reimbursing, market access and promotional compliance. FarmavitaR+ is brand name of Farmavita Regulanet Ltd. Visit https://farmavitar.com for more information. Outsource anything you can think of!


    International Pharmaceutical Industry

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    http://www.ipimediaworld.com

    IPI gives you an insight into all areas of Biopharm, Medical, Pharmaceutical and Healthcare. IPI provides a proven supportive means of communication to the Pharmaceutical, Bio Pharmaceutical, Nutraceutical and Medical Devices industry, incorporating the latest in research and technology innovations, regulatory guidelines, marketing and communication strategies.


    Swiss Biotech Association

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    http://www.swissbiotech.org/

    The Swiss Biotech Association (SBA) is the national industry association for biotechnology, including pharmaceuticals, diagnostics, agriculture, food, cosmetics, environmental biotechnology, and specialty chemicals. Members are companies active in modern biotechnology, such as R&D, Production, Marketing and Sales, Finance, Services and Consulting. SBA provides a networking platform for Life Science clusters, academic and federal institutions the like. Founded in March 1998, the Association grows steadily.


    Contract Biotechnology

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    http://www.contract-biotechnology.com

    Contract-Biotechnology.com is a web-based platform for laboratory outsourcing solutions. It is an online R&D matching tool that connects Scientifics and service and product providers worldwide. The platform Contract-Biotechnology.com would help you in the process of finding the right partner saving time and money, because with one single and secure application you would be able to receive multiple quotes quickly, keeping your contact information confidential. Contract-Biotechnology.com is the new Collaboration Network Model for Discovery Research and Development. Contract-Biotechnology.com team has extensive experience working for pharmaceuticals, biotechs, universities and academic research institutes and can help you addressing your key gaps.


    GBI

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    http://www.gbihealth.com/

    GBI is an information, applications, and services company focused on the healthcare industry. Leveraging data from across the healthcare value chain, GBI creates web and mobile applications that enable individuals and organizations to make better decisions and communicate more effectively.


    Biocompare

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    http://www.biocompare.com

    Biocompare.com is the leading resource for up-to-date product information, product reviews, and new technologies for life scientists. Biocompare combines an in-depth knowledge of life science products and new technologies with the power of the Internet to offer scientists the most dynamic, relevant, and innovative media-based marketplace for life science information.


    Biosave

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    Biosave.com brings together the best Life Science promotions, product releases, featured products, publications, videos and events from 100’s of leading Life Science suppliers. Updated 24 hours a day, Biosave is constantly uploading special promotions and exciting product news that you won’t find anywhere else. Our goal is to provide our users with the most exclusive product information to help reach that all important purchasing decision.


    Pharmavision

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    http://www.pharmavision.co.uk

    PharmaVision offers a consultancy service providing independent pharmaceutical thematic research to the healthcare industry, the investment community and competitive intelligence specialists. We perform due diligence research and provide expert commentary in healthcare. Our reports combine scientific analysis in drug delivery, R&D technologies and pharmaceutical products including patient modelling, product/technology forecasts and market trends evaluation.


    Pharmalicensing

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    http://www.pharmalicensing.com

    Pharmalicensing (www.pharmalicensing.com) is the premier biopharmaceutical Open Innovation resource designed for professionals involved with partnering, licensing and business development worldwide. Actively supporting all forms of partnering and in- and out-licensing activities, Pharmalicensing utilizes the unique online Showcase Profiling & Discover services, as well as its renowned Partnering Search service leveraging its global network of industry experts, to enable companies to identify and engage with appropriate partners around the world. Pharmalicensing is actively utilized by many tens of thousands of industry professionals each month. Pharmalicensing is a division of Cognis Group, Inc.


    SciDoc Publishers

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    SciDoc Publishers is a major source provider of e-journals in the field of Science, Technology and Medicine (STM). The nature of journals - Open Access and Peer-reviewed. We are aimed with a sole motive in making a mark in the field of Open Access, by propagating the knowledge to the scientific community. Our prime concern involves, the knowledge to reach millions of readers and give them access to scientific publications - online.


    Pharmaceutical Technology

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    Pharmaceutical-technology.com is the only website focusing specifically on issues relevant to pharmaceutical professionals working with technology, be it development, engineering, IT or production. Pharmaceutical-technology.com brings you the latest in industry projects and updates, along with the news, views and trends that leading professionals – from senior executives to manufacturing managers and heads of procurement – require to stay on top of their field.


    Gate2Biotech

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    Gate2Biotech is a portal that unites biotechnological community in Central Europe. It covers all the news in the field of biotechnology. Thanks to the the portal the companies engaged in the field can easily search for research institutions and other partners to solve technical problems they are facing and here they can also present their services offer to potential partners from the Czech Republic and abroad. Gate2Biotech portal serves as a bridge connecting scientific and commercial sector. It incorporates offices and support organizations dedicated to promoting transfer of innovative technologies into a unified communication platform of Czech and international biotechnologies. As a mediator of information it draws attention to biotechnologies and support of their application and transfer into practice. It also functions as a tool for encouraging non-professionals (especially scientists and students) towards innovative business or applied research.


    Technology Networks

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    Founded in 2000, Technology Networks is established as the leading news provider for life science and drug discovery professionals. In addition, we provide unique content including webcasts, videos, application notes and posters from recent conferences. Our portfolio now includes around 30 focussed scientific communities, all of which are accessible free of charge within TechnologyNetworks.com


    Drug Development Technology

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    Drugdevelopment-technology.com covers every aspect of the drug development and research process, from conception to pre-FDA approval. Our global network of journalists updates the site with the latest and most significant industry developments. This coverage allows us to provide everyone - from senior management through to research and QA staff – with in-depth reviews of the latest projects, advance notice of new product releases and analysis of the latest procedural and legislative developments.


    Pharmacircle

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    http://www.pharmacircle.com

    PharmaCircle is an innovative knowledge management company serving the current and future global leaders in the Pharmaceutical and Biotechnology related industries. PharmaCircle is a one stop information and analysis source for pipeline, products, clinical trials, drug delivery technologies, deals and acquisitions, company financials, venture capital investments, product sales, pharmaceutical services, news, patents and more….


    Drug Discovery Today

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    Drug Discovery Today covers the whole of the preclinical drug discovery process. The reviews are cutting edge, written by experts in their respective fields and cover all aspects of drug discovery from genomic and proteomic approaches, computational drug design, medicinal chemistry and the translation of these sciences to therapies.


    Mednous

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    http://www.MedNous.com

    MedNous is a print publication and website about medical innovation in Europe. It carries exclusive interviews with companies that are at the forefront of medical technology, as well as contributor articles from prominent practitioners. Our mission is to identify significant advances in medicine and to explain how this innovation is being commercialised. In doing so, we talk to venture capitalists about what products and platforms they are supporting. We report on how regulators cope with the accelerating pace of innovation. And we regularly cover the latest developments in the discovery and development of new medical concepts in the area of antibodies, vaccines, small molecules, regenerative medicine and nanomedicines. MedNous combines the English word for medicine with the Greek word for intellect. And those with nous are readers of our publication. Visit our website: www.mednous.com

    Copthorne Tara Hotel

    Scarsdale Place
    Kensington
    London W8 5SR
    United Kingdom

    Copthorne Tara Hotel

    The Copthorne Tara Hotel London Kensington is an elegant contemporary four-star hotel in prestigious Kensington, located just a two minutes walk from High Street Kensington underground station, making exploring easy. The hotel offers well-appointed and comfortable guest rooms combining Standard, Superior and Club accommodation. Club rooms offer iconic views over the city and include Club Lounge access for complimentary breakfast and refreshments. Guests can sample the authentic Singaporean, Malaysian and Chinese cuisine at Bugis Street, traditional pub fare at the Brasserie Restaurant & Bar or relax with a delicious drink at West8 Cocktail Lounge & Bar.

    The Copthorne Tara Hotel boasts 745 square meters of flexible meeting space, consisting of the Shannon Suite and the Liffey Suite, ideal for hosting conferences, weddings and social events. Facilities include access to the business centre 24 hours a day, fully equipped fitness room, gift shop, theatre desk and Bureau de Change. With ample onsite parking outside the London congestion charge zone and excellent transport links via Heathrow Airport, the hotel is the perfect location for business or leisure stays. The hotel is within close proximity to the shops of High Street Kensington, Knightsbridge and Westfield London, Olympia Conference Centre, Royal Albert Hall, Kensington Palace and Hyde Park.

     

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    WHAT IS CPD?

    CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

    ‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

    CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

    Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

    CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

    CPD AND PROFESSIONAL INSTITUTES

    There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

    For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

    CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

    TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

    Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

    ‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

    ‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

    The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

    As a formal provider of CPD certified activities, SAE Media Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

    GLOBAL CPD

    Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

    CPD Certificates

    We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@saemediagroup.com

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