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ADC Development
6 December 2012
ADC Development

This unique masterclass will provide a complete overview into the current developments in the ADC field, and attendees will be presented with real case studies on the latest in ADC conjugation and linker research. This event will explore the latest technological and scientific updates and will act as a unique forum for debate and problem-solving discussion on real examples of conjugation strategies and synthesis techniques for successful antibody-drug conjugate production.

Led by the expertise of Mahendra Deonarain, Chief Scientific Officer, and Gokhan Yahioglu, Director of Chemistry, PhotoBiotics this masterclass will be the perfect platform for networking and knowledge sharing with key industry representatives in this fast developing field.

 

Masterclass agenda

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8:30

Registration and Coffee

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9:00

Welcome and Introductions

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9:10

A review of ADCs: Antibody formats, linkers and drugs

Examples:

  • Whole antibodies, fragments, alternative scaffolds.
  • Tubilin inhibitors, photosensitisers, DNA damaging agents
  • Cleavable and non-cleavable linkers
  • clock

    9:55

    Drug Syntheses: How do you make drugs ready for bioconjugation?

    Examples:

  • Organic syntheses of photosensitisers
  • Addition of solubilising groups
  • Addition of linkers
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    10:40

    Coffee Break

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    10:55

    Antibody-Drug conjugation strategies

  • Buffers and conditions
  • Amino acid positions
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    11:30

    Analyses of ADCs

  • Spectroscopic: Mass Spec and HPLC
  • Cell uptake and kill studies
  • Animal models
  • clock

    12:00

    Discussion

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    12:30

    End of Masterclass

    Holiday Inn Bloomsbury

    Coram Street
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    United Kingdom

    Holiday Inn Bloomsbury

    Holiday Inn London-Bloomsbury is just 2 minutes' walk from the Tube at Russell Square station, for speedy connections across the capital. We're 10 minutes by bus from Eurostar connections at St Pancras station, and a 45-minute taxi ride from London Heathrow Airport. Check into your stylish Guest room, air-conditioned and connected to wireless Internet.

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    WHAT IS CPD?

    CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

    ‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

    CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

    Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

    CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

    CPD AND PROFESSIONAL INSTITUTES

    There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

    For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

    CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

    TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

    Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

    ‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

    ‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

    The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

    As a formal provider of CPD certified activities, SAE Media Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

    GLOBAL CPD

    Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

    CPD Certificates

    We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@saemediagroup.com

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