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Long-acting Platforms in Ocular Drug Delivery
24 November 2021
Long-acting Platforms in Ocular Drug Delivery

SAE Media Group proudly presents the 4th Annual Ophthalmic Drugs Conference Workshop Day taking place on the 24th November 2021, in London.

The global ophthalmic drug market is forecast to surpass $60 billion USD by 2025 with increasing focus from the industry on alternative delivery approaches and improving the effectiveness of the current repertoire of drugs in order to grow away from intravitreal injections and other surgical approaches to ocular therapy. With 50% of the global population predicted to have complications in their sight within the next few decades, ophthalmic medicine is set to become one of the biggest industries in pharmaceuticals.

In this workshop, challenges associated with different delivery systems and routes of administration will be explored. The benefits and challenges in the design of long-acting (LA) drug delivery systems will be analysed. In this session we will also use tangible examples of both ocular and non-ocular LA technologies that have been successfully launched in the market. Finally, it will focus on the design space of LA technologies for small molecules vs biologics and the applicability of devices in the delivery of LA formulations.

FEATURED SPEAKERS

Laurence  Fitzhenry

Laurence Fitzhenry

Lecturer & Project Coordinator, ORBITAL-ITN
Thakur Raghu Raj Singh

Thakur Raghu Raj Singh

Professor in Pharmaceutics, Founder and CTO Re-Vana Therapeutics, Chair for Ocular Delivery Focus Group, Queen's University Belfast

Laurence Fitzhenry

Lecturer & Project Coordinator, ORBITAL-ITN
Laurence  Fitzhenry

Dr. Laurence Fitzhenry is a Lecturer in Chemistry at the Department of Science, Waterford Institute of Technology and Principal Investigator of the Ocular Therapeutics Research Group (OTRG) at the PMBRC.
He received his PhD in polymer and analytical chemistry from WIT in 2011, where he conducted his postdoctoral research on the development of contact lenses for the controlled release of pharmaceutical actives.
Laurence is the project co-ordinator for the MSCA-funded ORBITAL-ITN, a global consortium focused on training researchers in the development of innovative strategies for posterior segment drug delivery to the eye.
 

Thakur Raghu Raj Singh

Professor in Pharmaceutics, Founder and CTO Re-Vana Therapeutics, Chair for Ocular Delivery Focus Group, Queen's University Belfast
Thakur Raghu Raj Singh

Dr Raj Thakur is a Reader in Pharmaceutics at the School of Pharmacy, QUB and is the Co-founder & CTO of Re-Vana Therapeutics. His research interest is in the design and physicochemical characterisation of advanced long-acting biodegradable drug delivery systems including medical devices for localised drug delivery. He is the Chair for Ocular Drug Delivery (OcDD) Focus Group supported by the mission of Controlled Release Society (CRS). He has authored over 165 scientific publications, including 55 full papers, 10 book chapters, five textbooks, several invited talks in national and international conferences and patents.

Workshop agenda

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8:30

Registration & Coffee

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9:00

Opening remarks and introductions

Thakur Raghu Raj Singh, Professor in Pharmaceutics, Founder and CTO Re-Vana Therapeutics, Chair for Ocular Delivery Focus Group, Queen's University Belfast

Laurence Fitzhenry, Lecturer & Project Coordinator, ORBITAL-ITN

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9:10

Understanding the challenges of ocular drug delivery

  • This initial session will prioritise delivery of therapeutics to the anterior and posterior segment of the eye.
  • The session will also review the most pressing challenges faced in ocular drug delivery.
  • Thakur Raghu Raj Singh, Professor in Pharmaceutics, Founder and CTO Re-Vana Therapeutics, Chair for Ocular Delivery Focus Group, Queen's University Belfast

    Laurence Fitzhenry, Lecturer & Project Coordinator, ORBITAL-ITN

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    10:00

    What have we learnt from existing LA systems?

  • During this session we will review the opportunities and drawbacks for in vitro testing
  • Assessing the limitations surrounding regulations in the evaluation of LA drug delivery systems
  • Thakur Raghu Raj Singh, Professor in Pharmaceutics, Founder and CTO Re-Vana Therapeutics, Chair for Ocular Delivery Focus Group, Queen's University Belfast

    Laurence Fitzhenry, Lecturer & Project Coordinator, ORBITAL-ITN

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    10:30

    Morning Coffee

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    11:00

    Analysis of current challenges in the design of LA drug delivery systems loaded with small molecules vs large molecules

  • In this session we will discuss current possibilities and constraints in the design of an LA system for the delivery of therapeutics to the ocular environment.
  • Thakur Raghu Raj Singh, Professor in Pharmaceutics, Founder and CTO Re-Vana Therapeutics, Chair for Ocular Delivery Focus Group, Queen's University Belfast

    Laurence Fitzhenry, Lecturer & Project Coordinator, ORBITAL-ITN

    clock

    11:50

    Future gazing: a look into the next generation of delivery platforms

  • During this session we will review recent developments of both new ocular therapeutics LA systems under clinical investigations and other new technologies on the horizon
  •  

    Thakur Raghu Raj Singh, Professor in Pharmaceutics, Founder and CTO Re-Vana Therapeutics, Chair for Ocular Delivery Focus Group, Queen's University Belfast

    Laurence Fitzhenry, Lecturer & Project Coordinator, ORBITAL-ITN

    clock

    12:20

    Closing Remarks

    Thakur Raghu Raj Singh, Professor in Pharmaceutics, Founder and CTO Re-Vana Therapeutics, Chair for Ocular Delivery Focus Group, Queen's University Belfast

    Laurence Fitzhenry, Lecturer & Project Coordinator, ORBITAL-ITN


    Lecturer & Project Coordinator
    ORBITAL-ITN
    Professor in Pharmaceutics, Founder and CTO Re-Vana Therapeutics, Chair for Ocular Delivery Focus Group
    Queen's University Belfast

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