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Device Possibilities for Future Inhaled Therapies
20 April 2010
Device Possibilities for Future Inhaled Therapies

Inhalation devices used in asthma therapy have continually evolved and should comprise of powder and liquid devices with good performance. Future development of these devices is still needed and their performance will improve as the regulatory landscape sharpens requirements. This follows a path taken by the regulatory agencies but also will be an outcome of new therapies with more sensitive API’s and a subsequent need for better dosing accuracy and range. This workshop will look into the options that are available for future inhalation drug delivery. There will be a strong focus on device/formulation interaction possibilities and limitations along with some thoughts on the patient interaction and patient interface systems.

 


 Workshop Agenda:

What device classes are available?

  • Compatibility with new drug development (biologics, antibodies etc)

Formulation considerations

  • What options and limitations are there for new entities?
  • How will new entities influence the formulation?

Performance possibilities and limitations

  • Can new entities be formulated to fit the device an give good performance?

Patient interaction

  • Compliance - can it be improved?
  • Effects of the breathing manouvre

 


 About the Workshop Leader:

  Dr. Ola Nerbrink has been active in the pharmaceutical field for more than 24 years and is today the owner of Respiron Consulting, a consultancy with a speciality in early development of inhalation devices and their interaction with formulation. He was initially employed at AstraZeneca R&D, Lund, Sweden in 1985 with focus on development and characterisation of inhalation systems based on DPI’s, nebulisers and pMDI’s, acquiring a broad knowledge and business contact surface of the providers of available inhalation technologies. From 2002 to 2009 he was employed at Novo Nordisk in Hillerød, Denmark as a specialist in inhalation systems. With his theoretical and practical knowledge, Ola Nerbrink will give attendees of this workshop a valuable insight into the options and possibilities that exist in the future of inhalation therapy.

 


 

Workshop agenda

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13:30

Registration & Coffee

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14:00

Introduction

  • Outline and content
  • clock

    14:15

    Device Options

  • Grouping of devices (classes)  
  • What devices are avialable in each group
  • How can they be expected to work with new entities (liquid vs powder)
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    15:00

    Formulation Considerations for Different Devices

  • Liquid or powder; pros and cons
  • Available excipients vs new excipients; what to expect and do
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    15:45

    Afternoon Tea

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    16:00

    Device Performance Options and Limitations

  • Drivers for optimal performance
  • What limits the performance
  • clock

    16:45

    Patient Interaction and Considerations

  • Can we get better compliance and if so how
  • How is the dose delivery affected by the bteathing manouvre
  • clock

    17:15

    Conclusions

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    17:30

    Close of Workshop

    Marriott Hotel Regents Park

    128 King Henry’s Road
    London NW3 3ST
    United Kingdom

    Marriott Hotel Regents Park

    This 4 star north London hotel in zone 2 is the perfect destination for the astute business traveler as well as the leisure guest that knows how convenient north London hotels are, as a base from which to explore the city .Bond Street is just 3 stops from Swiss Cottage underground station on the Jubilee Line, so you can be shopping, exploring the sights and taking in one of London’s world-renowned West End shows in less than 15 minutes when you stay at this hotel near central London. At the same time, the hive of activity that is Camden Town, the chic shops, cafes and restaurants of Primrose Hill and ZSL’s London Zoo in Regents Park are all just a short walk from this hotel in north London.

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