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Advances and Progress in Drug Design
15 February - 16 February 2016
Advances and Progress in Drug Design

SAE Media Group presents the 15th Annual Advances and Progress in Drug Design 2016, with a strong focus on advanced biophysical technologies and combinatorial methods enabling greater insight of biologics and drug interaction. 
Hosted over two days, this international conference will provide an exclusive opportunity to gain new insight on small molecule-protein fragments, IMI Open PHACTS project for data mining work flows, and structure-based models combining hit finding strategies of fragment leads.
Inspiring talks will also highlight developments in the quality control of misfolded proteins, solvent effects, and protein-ligand stability; identifying whether the bound conformation of protein-ligand structure gives the lowest energy state and the impact of drug design.

Join us for a keynote address on reviving covalent drug design in oncology from Pfizer, and a case study session on target validation of NCE’s through fragment screening and opportunities for antibodies as guidance tools from UCB.
 

FEATURED SPEAKERS

Armin  Ruf

Armin Ruf

Section Head Biostructure, Roche
Doug Johnson

Doug Johnson

Research Fellow, Pfizer
Gianni Chessari

Gianni Chessari

Director, Astex Pharmaceuticals
Gregg Siegal

Gregg Siegal

Chief Executive Officer, ZoBio
Hans Matter

Hans Matter

Senior Scientist, Sanofi-Aventis
Herman van Vlijmen

Herman van Vlijmen

Senior Director, Janssen
Matthias Frech

Matthias Frech

Director, Merck KGaA

Alexander Hillisch

Director, Medicinal Chemistry , Bayer
Alexander Hillisch

Alexey Rak

Head of Bio Structure & Biophysics, Sanofi
Alexey Rak

Armin Ruf

Section Head Biostructure, Roche
Armin  Ruf

Attilla Ting

Computational Chemist, AstraZeneca
Attilla Ting

Benjamin Tehan

Senior Computational Chemist, Heptares Therapeutics
Benjamin Tehan

Doug Johnson

Research Fellow, Pfizer
Doug Johnson

Gianni Chessari

Director, Astex Pharmaceuticals
Gianni Chessari

Gregg Siegal

Chief Executive Officer, ZoBio
Gregg Siegal

Hans Matter

Senior Scientist, Sanofi-Aventis
Hans Matter

Herman van Vlijmen

Senior Director, Janssen
Herman van Vlijmen

Howard Feldman

Principal Scientist, Chemical Computing Group
Howard  Feldman

Jordi Munoz Muriedas

Investigator, GSK
Jordi Munoz Muriedas

Manuel Molina

Research Scientist, Eli Lilly
Manuel  Molina

Marta Westwood

Principal Scientist, UCB Pharma
Marta Westwood

Matthias Frech

Director, Merck KGaA
Matthias Frech

Mike Hann

Director, Computational & Structural Sciences, GlaxoSmithKline
Mike Hann

Paul Hawkins

Applications Science Group Leader, OpenEye Scientific Software
Paul Hawkins

Simone Fulle

Research Group Leader, BioMed X Innovation Center
Simone Fulle

Stevan Djuric

Senior Director Discovery Chemistry and Technology, AbbVie
Stevan Djuric

Xavier Barril

ICREA Research Professor, Barcelona University
Xavier Barril

sponsors

Conference agenda

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8:30

Registration & Coffee

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9:00

Opening remarks and introductions

Xavier Barril

Xavier Barril, ICREA Research Professor, Barcelona University

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9:10

Kinetics vs thermodynamics: a question of perspective

Xavier Barril

Xavier Barril, ICREA Research Professor, Barcelona University

·         Importance of kinetics

·         Association/dissociation pathways

·         Structural factors that affect the kinetic behaviour

 

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9:50

Water molecules and binding hot spots

Xavier Barril

Xavier Barril, ICREA Research Professor, Barcelona University

·         The dynamic behavior of solvent molecules

·         Identification of binding hot spots using dynamic information

 

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10:30

Morning Tea

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11:00

Practical aspects of MD simulations

Xavier Barril

Xavier Barril, ICREA Research Professor, Barcelona University

·         Introduction to MD

·         Real time, simulated time, computing time

·         Examples of reliable MD applications for drug design

 

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12:20

Closing remarks

Xavier Barril

Xavier Barril, ICREA Research Professor, Barcelona University

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12:30

Close of workshop

Xavier Barril

Xavier Barril, ICREA Research Professor, Barcelona University

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13:30

Registration

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14:00

Opening remarks and introductions

Emma Blaney

Emma Blaney, Senior Programme Manager, C4X Discovery Limited

Martin  Watson

Martin Watson, Head of NMR, C4X Discovery Limited

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14:10

Conformational design in drug discovery

- Introduction to molecular conformation

- Principles and objectives of conformational design

 

Emma Blaney

Emma Blaney, Senior Programme Manager, C4X Discovery Limited

Martin  Watson

Martin Watson, Head of NMR, C4X Discovery Limited

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14:50

C4X NMR analysis

- Outline of data collection and analysis

- Conformational model and descriptions

- Example structural analyses

 

Emma Blaney

Emma Blaney, Senior Programme Manager, C4X Discovery Limited

Martin  Watson

Martin Watson, Head of NMR, C4X Discovery Limited

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15:30

Afternoon Tea

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16:00

Case Studies and discussion session

- Interrogate how conformational insight can improve pharmacophore models

- Investigate how conformational design can improve selectivity profiles

 

Emma Blaney

Emma Blaney, Senior Programme Manager, C4X Discovery Limited

Martin  Watson

Martin Watson, Head of NMR, C4X Discovery Limited

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16:20

Topic Heading 8

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17:20

Closing remarks

Emma Blaney

Emma Blaney, Senior Programme Manager, C4X Discovery Limited

Martin  Watson

Martin Watson, Head of NMR, C4X Discovery Limited

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8:30

Registration & Coffee

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9:00

Chairman's Opening Remarks

Gregg Siegal

Gregg Siegal, Chief Executive Officer, ZoBio

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9:10

OPENING ADDRESS: Using Biophysics to Drive Drug Discovery

Gregg Siegal

Gregg Siegal, Chief Executive Officer, ZoBio

  • Enabling proteins for biophysics and structural biology
  • Detecting and characterizing small molecule-target interactions with biophysics
  • The complementarity of NMR and X-ray for structural information
     
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    9:50

    A toolbox for fragment optimisation

    Gianni Chessari

    Gianni Chessari, Director, Astex Pharmaceuticals

  • Are all protein-fragment interactions favourable? 
  • Is the bound conformation a low energy geometry?
  • Where do I grow my fragment?
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    10:30

    Morning Coffee

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    11:00

    Organizing 3D project data for structure-based drug design

    Howard  Feldman

    Howard Feldman, Principal Scientist, Chemical Computing Group

      

  • Organise disparate crystallographic project data into a common homogeneous format
  • Automatically keep up-to-date
  • Perform family-based structure searches and homology modeling
  •  

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    11:40

    KEYNOTE ADDRESS: Reviving covalent drug design: Discovery of PF-04457845, an irreversible FAAH inhibitor with exquisite selectivity

    Doug Johnson

    Doug Johnson, Research Fellow, Pfizer

  • The unique benefits of small molecule covalent drug candidates
  • Activity-based protein profiling and clickable probes to evaluate selectivity of covalent binding
  • Biomarkers and PET ligand to determine target engagement in humans
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    12:20

    Networking Lunch

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    13:30

    Exploring uncharted kinome territory by mining structural information

    Simone Fulle

    Simone Fulle, Research Group Leader, BioMed X Innovation Center

  • Prioritizing kinase structures for drug discovery efforts
  • Dealing with protein flexibility
  • Mining selectivity determining features in binding sites
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    14:10

    Design and utility of compound libraries derived from High Throughput Chemistry in the Lead Optimization process

    Stevan Djuric

    Stevan Djuric, Senior Director Discovery Chemistry and Technology, AbbVie

    ·          Generation and and implementation of chemoinformatic tools for the design and production of high throughput chemical libraries

    ·          DOE tools for reaction “scouting” on a flow based library production platform

     

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    14:50

    Getting the right pose; where is the signal?

    Paul Hawkins

    Paul Hawkins, Applications Science Group Leader, OpenEye Scientific Software

  • Pose prediction in lead optimization is a challenging problem.
  • Generating a confidence in a predicted pose is more difficult still.
  • Protein flexibility is difficult to model.
  • Solution: improve performance and reliability by consuming all the relevant experimental information in the pose calculation.
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    15:30

    Afternoon Tea

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    16:00

    eHOMO calculations as a predictor for mutagenesis propensity of compounds

    Jordi Munoz Muriedas

    Jordi Munoz Muriedas, Investigator, GSK

  • HOMOlogate” your compounds to understand their mutagenic risk
  • Use it as a tool to improve interpretation of mechanisms driving mutagenicity
  • Use it as a tool to improve communication between safety and lead optimisation
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    16:40

    Linked open data in drug discovery: where are we?

    Herman van Vlijmen

    Herman van Vlijmen, Senior Director, Janssen

  • The IMI Open PHACTS project: status and outlook 
  • Data mining workflows using linked open data
  • A pharma challenge: merging public and private data
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    17:20

    Chairman’s Closing Remarks and Close of Day One

    Gregg Siegal

    Gregg Siegal, Chief Executive Officer, ZoBio

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    17:30

    Sponsored Drinks Reception

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    8:30

    Registration & Coffee

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    9:00

    Chairman's Opening Remarks

    Gregg Siegal

    Gregg Siegal, Chief Executive Officer, ZoBio

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    9:10

    OPENING ADDRESS: Structure-based drug discovery inspired by fragments: Methods, design and binding affinity

    Fragments combined with structure-based design play an important role in today’s drug discovery. The use of fragment-derived building blocks as seeds for further design will be illustrated in this contribution.

  • A fragment deconstruction approach will be presented to explore the super-additivity of fragment linking in protein-ligand complexes. By connecting two fragments with a single bond for serine protease inhibitors, a high linker contribution with significant improvement in affinity was observed.
  • Scoring functions are models for estimating the strength of non-covalent interaction. Key is a fundamental understanding of favourable and unfavorable protein-ligand interactions. Some tailoring towards fragments and lead-series will be shown.
  • Interaction of halogen atoms to binding sites has also consequences for affinity. Some interaction components of fragment contacts to aryl-rings, halogen-bonding and binding-site desolvation will be discussed. As classical force-fields cannot account for halogen-mediated interactions due to missing treatment of the “sigma”-hole, local properties from quantum-mechanical techniques that do not suffer from these limitations, will be presented.
  •  
     

    Hans Matter

    Hans Matter, Senior Scientist, Sanofi-Aventis

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    9:50

    Water mapping on drug design

    Benjamin Tehan

    Benjamin Tehan, Senior Computational Chemist, Heptares Therapeutics

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    10:30

    Morning Coffee

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    11:00

    Structure based drug design of the first known inhibitors of PHGDH

    Attilla Ting

    Attilla Ting, Computational Chemist, AstraZeneca

  • Multiple hit finding strategies conducted in parallel including directed libraries, HTS and fragment based lead generation for this challenging target
  • X-ray structures give unique insight to the binding mode and enable structure based design
  • Application of biophysic methods - NMR, biacore and ITC to aid prioritization and characterisation of hits and lead to delivery of first known PHGDH inhibitors
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    11:40

    Growing a baby: identifying and optimising quality leads and overcoming restraints in drug discovery

    Manuel  Molina

    Manuel Molina, Research Scientist, Eli Lilly

  • Evolution of fragment –derived chemical leads in comparison to alternative methods
  • Enabling biophysical technologies in drug discovery
  • Bridging different approaches in drug design to identify and optimise meaningful drug lead compounds.
  • Opportunities in biophysical screening to catch up with FBDD techniques
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    12:20

    Networking Lunch

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    13:30

    Atomic resolution for drug discovery

    Armin  Ruf

    Armin Ruf, Section Head Biostructure, Roche

  • How to get high resolution X-ray diffraction
  • General benefits for computer aided design
  • Atomic resolution structures of fragment screening hits

     

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    14:10

    Predicting ADMET and potency in drug design

    Alexander Hillisch

    Alexander Hillisch, Director, Medicinal Chemistry , Bayer

  • In silico ADMET prediction platform @ Bayer
  • Selected models: pKa prediction
  • Prediction of binding affinity to target proteins
  • Free energy perturbation
  • Application examples
  • Compound prioritization in large chemical optimization space
     
     
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    14:50

    Fragment-based approach at UCB

    Marta Westwood

    Marta Westwood, Principal Scientist, UCB Pharma

  • Targeting Protein-Protein Interactions (PPIs): challenges
  • Prosecuting PPI using Fragment-Based approach
  • Choosing targets for NCE programmes
  • Fragments at UCB
  • Fragment screening capacity at UCB - Fragment Screen of 12 PPI targets
  • Identifying reliable chemical starting points-screening cascade triage
  • Antibodies as tools to find new chemical matter
  •  

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    15:30

    Afternoon Tea

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    16:00

    Biophysical screening tools for compound validation

    Alexey Rak

    Alexey Rak, Head of Bio Structure & Biophysics, Sanofi

  • Small molecule probes to elucidate structural information and early validation
  • Tackling sensitivity issues in small-molecule ligand screening to generate lead hits
  • Integrated approaches for fragment screening to increase robustness
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    16:40

    Assessment of binding kinetics and “slow-off” rates

    Matthias Frech

    Matthias Frech, Director, Merck KGaA

  • Optimisation of factors that control Kass and Kdiss rates
  • Assessing the effects of receptor binding kinetics on drug efficacy an duplications of side effects
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    17:20

    Moving in water: molecular simulations as enabling tools for hit and lead generation

    Xavier Barril

    Xavier Barril, ICREA Research Professor, Barcelona University

  • Molecular Dynamics (MD) simulations are becoming the workhorse of routine drug design applications.
  • Solvent and dynamic effects bring about a major improvement in the quality of the predictions
  • Applications to druggability assessment, binding site mapping and virtual screening will be presented
  •  

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    18:00

    Chairman’s Closing Remarks and Close of Day Two

    Gregg Siegal

    Gregg Siegal, Chief Executive Officer, ZoBio


    Director, Medicinal Chemistry
    Bayer
    Head of Bio Structure & Biophysics
    Sanofi
    Section Head Biostructure
    Roche
    Computational Chemist
    AstraZeneca
    Senior Computational Chemist
    Heptares Therapeutics
    Research Fellow
    Pfizer
    Director
    Astex Pharmaceuticals
    Chief Executive Officer
    ZoBio
    Senior Scientist
    Sanofi-Aventis
    Senior Director
    Janssen
    Principal Scientist
    Chemical Computing Group
    Investigator
    GSK
    Research Scientist
    Eli Lilly
    Principal Scientist
    UCB Pharma
    Director
    Merck KGaA
    Director, Computational & Structural Sciences
    GlaxoSmithKline
    Applications Science Group Leader
    OpenEye Scientific Software
    Research Group Leader
    BioMed X Innovation Center
    Senior Director Discovery Chemistry and Technology
    AbbVie
    ICREA Research Professor
    Barcelona University

    Sponsors and Exhibitors

    Supporting Media Partners

    Supporters

    Workshops

    A fresh view on molecular recognition: The dynamic perspective

    A fresh view on molecular recognition: The dynamic perspective

    Holiday Inn Kensington Forum
    17 February 2016
    London, United Kingdom

    Analysis and Application of Ligand Conformation in Drug Design

    Analysis and Application of Ligand Conformation in Drug Design

    Holiday Inn Kensington Forum
    17 February 2016
    London, United Kingdom

    List of 2016 Attendees

    Download

    Interview with Dr Xavier Barril, ICREA Research Professor, School of Pharmacy, Barcelona University

    Download

    Interview with Gregg Seigal, Chief Executive Officer, ZoBio

    Download

    Interview with Ben Tehan, Principle Computational Chemist, Heptares Therapeutics

    Download

    Sponsors and Exhibitors


    Chemical Computing Group

    Sponsors and Exhibitors
    http://www.chemcomp.com/

    CCG (Chemical Computing Group) is a leading supplier of software solutions for life sciences. With a proven track record in scientific innovation, CCG provides state-of-the-art applications in drug discovery to pharmaceutical, biotechnology and academic researchers. CCG headquarters are in Montreal (Canada), with support offices in North America, Europe and Asia.


    NanoTemper Technologies

    Sponsors and Exhibitors
    http://www.nanotemper-technologies.com/

    NanoTemper Technologies develops, produces and sells innovative instruments for biomolecular interaction analytics, with applications in basic research and the pharmaceutical and biotech industries. Headquartered in Munich, Germany with subsidiaries across the globe, NanoTemper is expanding rapidly. NanoTemper's high quality instruments are based on the proprietary and unique MicroScale Thermophoresis (MST) and nanoDSF technologies, as well as the recently acquired Surface Acoustic Wave (SAW) technology.


    OpenEye Scientific Software

    Sponsors and Exhibitors
    http://www.eyesopen.com/

    OpenEye has built a solid reputation as a scientific leader in the field of molecular design based on two decades of delivering useful applications and programming toolkits. Our scientific approach has focussed on the power of molecular 3D structure to inform and guide, in particular via the concept of shape similarity. We have changed industry perception of what is possible with the speed, robustness and scalability of our tools and have recently built these into a ground-up, cloud-native platform, Orion. Combining unlimited computation and storage with powerful tools for data sharing, visualization and analysis in an open development platform, Orion offers unprecedented capabilities for drug discovery and optimization.

    Media Partners


    International Journal of Computational Biology and Drug Design

    Supporting Media Partners
    http://www.inderscience.com/ijcbdd

    IJCBDD, an International Society of Intelligent Biological Medicine official journal, bridges the gap between two very important, complementary disciplines, computational biology and drug design. Through advances in high-throughput genome sequencing and digital imaging technologies, biocomputing, drug design and medical research have unfolded new, predictive sciences such as genomics, proteomics, lipidomics, metabolomics, cytomics and pharmaconomics. These promote new computational, statistical and biomedical approaches to drug design/development, besides unleashing the potential of significantly more accurate, effective personalised diagnosis, therapeutics and patient care.


    International Journal of Biotechnology

    Supporting Media Partners
    http://www.inderscience.com/ijbt

    IJBT provides an international forum and refereed authoritative source of information in the field of Biotechnology and Biotechnics, with emphasis on management and economics, as well as the political and social issues. It aims to disseminate knowledge, provide a learned reference in the field, and establish channels of communication between academic and research experts, policy makers and executives in industry, commerce and investment institutions.


    International Journal of Computational Intelligence in Bioinformatics and Systems Biology

    Supporting Media Partners
    http://www.inderscience.com/ijcibsb

    IJCIBSB is a fully refereed international research journal which provides a forum for papers describing cutting edge research in the application of artificial and computational intelligence to the field of bioinformatics and systems biology.


    International Journal of Biomedical Engineering and Technology

    Supporting Media Partners
    http://www.inderscience.com/ijbet

    IJBET addresses cutting-edge research in the multi-disciplinary area of biomedical engineering and technology. Medical science incorporates scientific/technological advances combining to produce more accurate diagnoses, effective treatments with fewer side effects, and improved ability to prevent disease and provide superior-quality healthcare. A key field here is biomedical engineering/technology, offering a synthesis of physical, chemical, mathematical and computational sciences combined with engineering principles to enhance R&D in biology, medicine, behaviour, and health. IJBET includes the Asia-Pacific Chapter in Biomedical Wireless Technology (APC-BWT).


    International Journal of Bioinformatics Research and Applications

    Supporting Media Partners
    http://www.inderscience.com/ijbra

    Bioinformatics is an interdisciplinary research field that combines biology, computer science, mathematics and statistics into a broad-based field that will have profound impacts on all fields of biology. The emphasis of IJBRA is on basic bioinformatics research methods, tool development, performance evaluation and their applications in biology. IJBRA addresses the most innovative developments, research issues and solutions in bioinformatics and computational biology and their applications.

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    Bioscreening

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    Innovations in Pharmaceutical Technology (IPT)

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    http://www.iptonline.com/

    Innovations in Pharmaceutical Technology (IPT) magazine offers in-depth comment and analysis written by experts from within the field. IPT covers the latest developments in drug discovery, laboratory technology, formulation, delivery systems, and other insights and innovations in the field. The magazine also presents sector-specific events, company and individual profiles, and reviews. IPT is a platform for those involved in pharmaceuticals and biotechnology to share their ideas with other key industry figures.

    Now you can also read IPT on the go with the new Samedan app. Click here to download the app for your iPhone or iPad: http://bit.ly/IJECug


    Drug Discovery Today

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    http://www.drugdiscoverytoday.com/

    Drug Discovery Today covers the whole of the preclinical drug discovery process. The reviews are cutting edge, written by experts in their respective fields and cover all aspects of drug discovery from genomic and proteomic approaches, computational drug design, medicinal chemistry and the translation of these sciences to therapies.


    Drug Development Technology

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    Drugdevelopment-technology.com covers every aspect of the drug development and research process, from conception to pre-FDA approval. Our global network of journalists updates the site with the latest and most significant industry developments. This coverage allows us to provide everyone - from senior management through to research and QA staff – with in-depth reviews of the latest projects, advance notice of new product releases and analysis of the latest procedural and legislative developments.


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    Inderscience is a dynamic, leading, independent journal publisher. The company disseminates the latest research across the broad fields of science, engineering and technology; management, public and business administration; environment, ecological economics and sustainable development; computing, ICT and internet/web services, and related areas. Inderscience offers over 35 years' experience in publishing and has succeeded in building a substantial collection approaching 400 high-quality peer-reviewed international research journals in both online and print formats. We offer a variety of ways to keep up-to-date with the latest published leading-edge research while our online collection represents a fully-searchable digital archive of around 60,000 articles.


    Biosave

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    The British Pharmacological Society (BPS) is the primary UK learned society concerned with research into drugs and the way they work. Our members work in academia, industry, regulatory agencies and the health services, and many are medically qualified. The Society covers the whole spectrum of pharmacology, including laboratory, clinical, and toxicological aspects. Clinical pharmacology is the medical speciality dedicated to promoting safe and effective use of medicines for patient benefit. Clinical pharmacologists work as consultants in the NHS and many hold prominent positions in UK Universities.


    Antibodies Online

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    antibodies-online.com facilitates researchers to find the appropriate antibodies for their respective research project. As an independent and multi-vendor marketplace for research antibodies and thanks to the cooperation with more than 130 different manufacturers, a large selection of Antibodies (over 700,000), ELISA Kits (over 130,000), Secondary Antibodies (17,000), Proteins (130,000), Peptides and Isotype Controls is available. By supporting the Independent Validation Initiative and the Resource Identification Initiative, antibodies-online.com also addresses the important topics of transparent product quality and scientific reproducibility. In addition scientists receive news and detailed information about the individual antibodies from databases such as the PubMed and others.


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    Swiss Biotech Association

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    Technology Networks

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    Founded in 2000, Technology Networks is established as the leading news provider for life science and drug discovery professionals. In addition, we provide unique content including webcasts, videos, application notes and posters from recent conferences. Our portfolio now includes around 30 focussed scientific communities, all of which are accessible free of charge within TechnologyNetworks.com


    Drug Discovery World

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    For over a decade DDW has continued to be the ‘must read’ journal within the DD&D Arena. DDW is recognised for voicing the opinions of some of the Industry’s leading luminaries and has become a recognised platform for Industry Gurus to debate some of the more challenging technological and business issues facing the the life science industry. DDW adheres to the maxim..... ‘Turning Science into Business’ DDW examines the advances in new technologies and the associated implications within the context of developing new and efficacious therapeutics. DDW is distinguishable in that it reaches out to a global audience at both bench and boardroom level, allowing both camps to profit from the uncomplicated style of editorial but at the same time challenges our readers to look at new ways to overcome discovery bottlenecks, embrace nascent technologies and build next generation technology platforms.


    Absave

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    Absave.com is the leading savings website for Antibodies and Immunological Products. Search our extensive database of Antibodies, Kits, Proteins & Peptides, Reagents, etc. to find the best savings!


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    Gate2Biotech

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    Frontiers in Clinical Drug Research - CNS and Neurological Disorders

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    Lab Bulletin is a free online resource for scientists and laboratory professionals where you can catch up on the latest news for laboratory products and services. You will find an extensive directory of laboratory suppliers and manufacturers enabling you to contact companies quickly and easily to request further information. Lab Bulletin also publishes four free monthly E-Newsletters keeping you up-to-date with all of the latest laboratory products and industry news directly to your inbox. We have dedicated E-Newsletters for Chromatography and Spectroscopy, Microscopy and Image Analysis, weekly Industry News updates and our monthly Lab Bulletin E-Newsletter sent out to over 29,000 readers worldwide. To request your free copy click here


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    PharmaVOICE magazine, and its supporting VIEW publications, provide commentary about the challenges and trends impacting the life-sciences industry, covering a range of issues from molecule through market. PharmaVOICE's more than 41,000 U.S.-based subscribers are also kept abreast of the latest trends through additional media resources, including WebSeminars, Podcasts, Videocasts, and White Papers.


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    Drug Target Review’s quarterly magazine, website and annual events program provides high quality content with peer-written articles that are submitted exclusively by the world’s most respected scientists in their field. This attracts a committed base of readers, users and delegates made up of senior decision-makers from the life science and drug discovery industries at the top pharmaceutical companies, as well as academics and scientists from the top research institutes across the globe.


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    Contract-Biotechnology.com is a web-based platform for laboratory outsourcing solutions. It is an online R&D matching tool that connects Scientifics and service and product providers worldwide. The platform Contract-Biotechnology.com would help you in the process of finding the right partner saving time and money, because with one single and secure application you would be able to receive multiple quotes quickly, keeping your contact information confidential. Contract-Biotechnology.com is the new Collaboration Network Model for Discovery Research and Development. Contract-Biotechnology.com team has extensive experience working for pharmaceuticals, biotechs, universities and academic research institutes and can help you addressing your key gaps.


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    SelectScience is an independent, online information resource for the worldwide scientific community, and the home of trusted information for laboratory scientists. Discover impartial, expert opinion and trusted reviews about latest laboratory equipment and techniques; plus videos, application notes and science news from around the world. Become a member for free today.

    Holiday Inn Kensington Forum

    97 Cromwell Road
    London SW7 4DN
    United Kingdom

    Holiday Inn Kensington Forum

    Holiday Inn Kensington Forum is perfectly situated in one of London’s most luxurious and beautiful areas within South Kensington. 

    The hotel is just 2 minutes walk from Gloucester Road tube station for convenient travel to Hyde Park, London Eye, Tower Bridge plus more of London’s top attractions. There are also easy and direct links to some major transport hubs including Victoria, Kings Cross St Pancras, Paddington and Heathrow. 

    This distinctive hotel in south London has so much to offer to make all guests really feel at home. The latest Holiday Inn relaunch is not just about the new look and feel for the hotel but to offer guests more benefits during their stay including a pillow menu for extra comfort during their sleep and a curved shower rail for more spacious feel. 

    In addition to our 906 rooms, all business guests can take advantage of our meeting and conference facilities including High Speed Internet Access and unlimited Starbucks coffee at The Academy. Our hotel’s professional event planners are on board to help take the hard work and stress away from planning your next event. 

    So whether you in London on business or pleasure, make the Holiday Inn London Kensington Forum your first choice of hotel and book your accommodation for our lowest internet rate guarantee. 

    HOTEL BOOKING FORM

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    WHAT IS CPD?

    CPD stands for Continuing Professional Development’. It is essentially a philosophy, which maintains that in order to be effective, learning should be organised and structured. The most common definition is:

    ‘A commitment to structured skills and knowledge enhancement for Personal or Professional competence’

    CPD is a common requirement of individual membership with professional bodies and Institutes. Increasingly, employers also expect their staff to undertake regular CPD activities.

    Undertaken over a period of time, CPD ensures that educational qualifications do not become obsolete, and allows for best practice and professional standards to be upheld.

    CPD can be undertaken through a variety of learning activities including instructor led training courses, seminars and conferences, e:learning modules or structured reading.

    CPD AND PROFESSIONAL INSTITUTES

    There are approximately 470 institutes in the UK across all industry sectors, with a collective membership of circa 4 million professionals, and they all expect their members to undertake CPD.

    For some institutes undertaking CPD is mandatory e.g. accountancy and law, and linked to a licence to practice, for others it’s obligatory. By ensuring that their members undertake CPD, the professional bodies seek to ensure that professional standards, legislative awareness and ethical practices are maintained.

    CPD Schemes often run over the period of a year and the institutes generally provide online tools for their members to record and reflect on their CPD activities.

    TYPICAL CPD SCHEMES AND RECORDING OF CPD (CPD points and hours)

    Professional bodies and Institutes CPD schemes are either structured as ‘Input’ or ‘Output’ based.

    ‘Input’ based schemes list a precise number of CPD hours that individuals must achieve within a given time period. These schemes can also use different ‘currencies’ such as points, merits, units or credits, where an individual must accumulate the number required. These currencies are usually based on time i.e. 1 CPD point = 1 hour of learning.

    ‘Output’ based schemes are learner centred. They require individuals to set learning goals that align to professional competencies, or personal development objectives. These schemes also list different ways to achieve the learning goals e.g. training courses, seminars or e:learning, which enables an individual to complete their CPD through their preferred mode of learning.

    The majority of Input and Output based schemes actively encourage individuals to seek appropriate CPD activities independently.

    As a formal provider of CPD certified activities, SAE Media Group can provide an indication of the learning benefit gained and the typical completion. However, it is ultimately the responsibility of the delegate to evaluate their learning, and record it correctly in line with their professional body’s or employers requirements.

    GLOBAL CPD

    Increasingly, international and emerging markets are ‘professionalising’ their workforces and looking to the UK to benchmark educational standards. The undertaking of CPD is now increasingly expected of any individual employed within today’s global marketplace.

    CPD Certificates

    We can provide a certificate for all our accredited events. To request a CPD certificate for a conference , workshop, master classes you have attended please email events@saemediagroup.com

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    Contact SAE Media Group

    UK Office
    Opening Hours: 9.00 - 17.30 (local time)
    SAE Media Group , Ground Floor, India House, 45 Curlew Street, London, SE1 2ND, United Kingdom
    Tel: +44 (0) 20 7827 6000 Fax: +44 (0) 20 7827 6001
    Website: http://www.smgconferences.com Email: events@saemediagroup.com
    Registered in England - SMi Group Ltd trading as SAE Media Group




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